Polyclonal Hyperviscosity Syndrome

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Polyclonal hyperviscosity syndrome in IgG4-related disease and associated conditions

Polyclonal hyperviscosity syndrome (HVS) is rare and has been reported in various disorders of immune dysregulation and lymphoid hyperplasia. IgG4-Related Disease (IgG4-RD) is an emerging disorder often associated with exuberant hypergammaglobulinemia, and this review of seven cases establishes IgG4-RD as an important cause of polyclonal HVS.

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Neonatal hyperviscosity syndrome.

THE HYPERVISCOSITY SYNDROME is a symptom complex associated with decreased blood fluidity, which is generally associated with an increase in erythrocyte mass. The mean cord blood hematocrit is 45±5% and 50 +5% in preterm and term infants respectively if they are born at sea level. Values are somewhat higher in infants born in locations at higher altitudes. A central venous hematocrit of 65% or ...

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The hyperviscosity syndrome.

common complication in IgG myeloma. Its occurrence has been ascribed to the presence in the serum of high molecular weight polymers of the IgG proteins. Three patients with IgG myeloma and the clinical hyperviscosity syndrome were investigated, none of whom had IgG polymers in the serum by analytical ultracentrifugation. Relative serum viscosity in these patients ranged from 10 to 17.4 (normal ...

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Hyperviscosity syndrome in patients with multiple myeloma.

A.W., a 50-year-old woman with a sixmonth history of frequent nosebleeds, was diagnosed with multiple myeloma. Before A.W. could meet with an oncologist, she presented to the emergency room with an uncontrollable nosebleed and spontaneous bleeding in her gums. Her menstrual period, which usually occurs over five or six days, lasted 10 with unusually heavy flow. A.W. also reported prolonged blee...

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Partial exchange transfusion for polycythemia hyperviscosity syndrome.

The objective of this study was to examine the use of partial exchange transfusion (PET) performed for polycythemia hyperviscosity syndrome (PHS) over time. A retrospective review of 141 infants who received a PET for PHS at Yale-New Haven Hospital between 1986 and 2007 was performed, querying maternal and neonatal medical records. Patient demographics, risk factors for PHS, indications for PET...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1977

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780200713